6-methyl-2H-pyrazolo[3,4-b]pyridin-3-amine - Names and Identifiers
Name | 6-Methyl-1H-pyrazolo[3,4-b]pyridin-3-amine
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Synonyms | 6 Methy1-1H-pyrazolo[3,4-6]pyridin-3-amine 6-Methyl-1H-pyrazolo[3,4-b]pyridin-3-amine 6-METHYL-2H-PYRAZOLO[3,4-B]PYRIDIN-3-AMINE 6 Methy1-1H-pyrazolo[3,4-6]pyridin-3-aMine 6-methyl-2H-pyrazolo[3,4-b]pyridin-3-amine 3-Amino-6-methyl-1H-pyrazolo[3,4-b]pyridine 1H-Pyrazolo[3,4-b]pyridin-3-aMine, 6-Methyl-
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CAS | 79173-38-9
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InChI | InChI=1/C7H8N4/c1-4-2-3-5-6(8)10-11-7(5)9-4/h2-3H,1H3,(H3,8,9,10,11) |
6-methyl-2H-pyrazolo[3,4-b]pyridin-3-amine - Physico-chemical Properties
Molecular Formula | C7H8N4
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Molar Mass | 148.17 |
Density | 1.50 |
Boling Point | 314 ºC |
Flash Point | 144 ºC |
Vapor Presure | 4.02E-06mmHg at 25°C |
Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
Refractive Index | 1.755 |
6-methyl-2H-pyrazolo[3,4-b]pyridin-3-amine - Risk and Safety
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
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HS Code | 29331990 |
Hazard Class | IRRITANT |
6-methyl-2H-pyrazolo[3,4-b]pyridin-3-amine - Introduction
6-Methyl-1H-pyrazolo[3,4-b]pyridin is an organic compound with the chemical formula C9H9N3.
Nature:
-Appearance: Colorless crystalline solid.
-Melting point: about 132-134°C.
-Solubility: It is easy to dissolve in polar solvents (such as chloroform, dimethylformamide), but has poor solubility in non-polar solvents (such as n-heptane).
Use:
6-Methyl-1H-pyrazolo[3,4-b]pyridin has certain applications in the field of drug research, and is often used as a pharmaceutical intermediate, especially an important structural module in tumor-related research and drug development.
Preparation Method:
6-Methyl-1H-pyrazolo[3,4-b]pyridin-3-amine can be synthesized by a variety of ways. One of the common methods is to react with concentrated sulfuric acid and orthochloropropionic anhydride to generate N-sulfonylpyrazole compound, and then electrophilic substitution reaction with p-methylaniline to obtain the target product.
Safety Information:
- 6-Methyl-1H-pyrazolo[3,4-b]pyridin has limited toxicity information, but as an organic compound, it should follow general laboratory safety practices.
-During use and storage, avoid contact with strong oxidants and strong acids to avoid dangerous reactions.
-In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help.
-in the process of operation should pay attention to avoid inhalation of its dust or steam, if necessary, to use personal protective equipment, such as laboratory coats, protective glasses and gloves.
Last Update:2024-04-09 15:18:00